ea0031oc2.2 | Steroids and thyroid | SFEBES2013
Madathil Asgar
, Hollingsworth Kieren
, Razvi Salman
, Blamire Andrew
, Taylor Roy
, Newton Julia
, Weaver Jolanta
Background: It is well established that subclinical hypothyroidism (SCH) is associated with mild ventricular dysfunction and early cardiovascular disease (CVD), but it is unknown if there is an underlying defect in cardiac bio-energetic function.Objective: To quantify the cardiac phosphocreatine/ATP (PCr/ATP) ratio in SCH, compare with healthy controls (HC) and to measure the effect of 6 months of thyroxine treatment.Method: Cardia...